p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation
نویسندگان
چکیده
منابع مشابه
p53 suppresses 14-3-3γ by stimulating proteasome-mediated 14-3-3γ protein degradation.
14-3-3 proteins are a family of highly conserved polypeptides that interact with a large number of proteins and play a role in a wide variety of cellular processes. 14-3-3 proteins have been demonstrated overexpressed in several cancers and serving as potential oncogenes. In a previous study we showed one isoform of the 14-3-3 family, 14-3-3γ was negatively regulated by p53 through binding to i...
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ژورنال
عنوان ژورنال: International Journal of Oncology
سال: 2014
ISSN: 1019-6439,1791-2423
DOI: 10.3892/ijo.2014.2740